Example of Nussinov’s algorithm in action. (Image Source)

Note: Before reading this article, read Sequence Alignment and the Needleman-Wunsch Algorithm to understand primary sequence alignment and dynamic programming; here, we extend our analysis to secondary RNA alignment through Nussinov’s Algorithm.

Terminology

A model of a person’s epigenome with relation to their DNA. (Image Source)

The Epigenome and Its Function

The human body has over 210 cell types, even though each one of those cells stores the same information inside of their DNA. How is this possible? The epigenome stores the information about the cell type and the state of the cell: it creates chemical modifications that influence gene expression.

A usage of PyMOL to show the 1IYJ BRCA2-DSS1 complex. (Image Source)

This article goes into how I used the visualization tool PyMOL for examining 3D representations of the aforementioned proteins, and looking into detail into various protein-protein and protein-DNA interactions.

Terminology

Aditya Mittal

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